Peptides have become common in skin care products, generally playing the role of relaxers for wrinkles.
However, these amino acid chains have untapped potential, ranging from soothing sensitivity to acne management to whitening hyperpigmentation.
Currently, the crystalline compound hydroquinone is considered the benchmark for skin lightening ingredients due to its proven ability to inhibit tyrosinase, an enzyme essential for the production of melanin. However, some doctors and patients are hesitant to use it because of its potential toxicity and its temporary or persistent side effects, although rare.
Some people have found limited success in researching unproven natural alternatives to hydroquinone, but a recent study published in the Journal of Investigative Dermatology highlights what can be an ideal and demonstrable substitute.
Researchers of two oligopeptides called P3 and P4 California Institute of Regenerative Medicine Elixir discovered that they not only bind to tyrosinase, like hydroquinone, but that they have no toxic effects. However, the evidence is even more impressive that these oligopeptides are 17 times more potent than hydroquinone.
The possibility of a less toxic and more effective alternative to hydroquinone is an interesting solution, but other steps must be taken before these oligopeptides can be applied in topical creams and serums.
Among these steps, there is the improvement of the ability of peptides to cross the skin barrier, which, interestingly, could be achieved using another type of peptide.