New discoveries indicate the theory that there may be a way to cause a slight increase in elastin production and to finally provide the last piece of the puzzle that doctors were looking for in the quest for youthful skin.
If injections have the potential to increase elastin in the skin, what does this mean for the next wave of fillers, like Juvéderm Volbella and Volift, which should be approved by the FDA in the near future?
Steven Fagien, suspects that diluting the product and injecting finer needles to direct the agent into the dermis (rather than below) are essential, but notes that It is not yet known how long the products must be in the skin to support the up regulation (signaling of production) of elastin.
“The future is the filling agents that do good to the skin in the short and long term to improve the quality of the skin. Maybe we will see injectables that act to pervert or restore what the skin has lost, like elastin.
According to Dr. Fagien, diluting the concentration of hyaluronic acid and making it suitable for injection into the dermis gives an effect similar to that of collagen loads. “When we did that, we saw something happening biologically to improve the skin.
“Dr. Fagien says that it was not the collagen that was created, but actually an upregulation of elastin. “We did not see this effect when we used hyaluronic acid, collagen stimulators or even collagen in their traditional methods.”
Although the longevity of the results (research is still in progress to explore the duration for which the hyaluronic acid injected produces elastin) has not been affected, there has been a marked improvement elastin fibers and glycosaminoglycans (the glue that holds collagen and elastin together). “For the first time, we refuted the theory of collagen and understood that what was missing from the skin over time was elasticity. The replacement of collagen gives volume to the skin, but it does not make it more flexible or elastic “, explains Dr. Fagien, adding that the skin has taken on a firmer, softer appearance and feeling and more elastic.